Incidence and influencing factors of healthcare-associated infection in pa-tients with nasopharyngeal carcinoma during radiotherapy period
10.3969/j.issn.1671-9638.2016.07.009
- VernacularTitle:鼻咽癌患者放疗期间医院感染发病率及影响因素
- Author:
Hui XUE
;
Aifeng MENG
;
Dejing XU
;
Yan WANG
;
Xiaoyu ZHENG
- Publication Type:Journal Article
- Keywords:
nasopharyngeal carcinoma;
healthcare-associated infection;
radiotherapy;
influencing factor
- From:
Chinese Journal of Infection Control
2016;15(7):481-483
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence and influencing factors of healthcare-associated infection (HAI) in inpatients with nasopharyngeal carcinoma during radiotherapy period.Methods The occurrence of HAI among patients with nasopharyngeal carcinoma in a tertiary first-class cancer hospital in Jiangsu Province between July 2012 and June 2014 were analyzed retrospectively.Results A total of 1 396 patients were investigated,the incidence of HAI was 2.29%,case incidence of HAI was 2.44%.The most common infection site was oral mucosa (n =24, 70.59%),and most infection occurred 2-4 weeks after the start of the radiotherapy.A total of 38 pathogenic iso-lates were isolated,24 (63.16%)were gram-positive bacteria,12 (31 .58%)were gram-negative bacteria,and 2 (5.26%)were fungi.Incidences of HAI were high in patients >50 years old,with chemotherapy,length of hospital stay>60 days,and used at least 2 kinds of antimicrobial agents (all P <0.05).Conclusion Prevention and control of HAI in patients with nasopharyngeal carcinoma during radiotherapy period should be strengthened,especially for the elderly,patients with chemotherapy,long length of hospital stay,and extensive use of antimicrobial agents.