Pharmaceutical Care for a Patient with Lung Cancer Complicated with Renal Insufficiency Receiving Pemetrexed Chemotherapy
10.3870/j.issn.1004-0781.2016.08.009
- VernacularTitle:1例肺癌并发肾功能不全患者接受培美曲塞化学治疗的药学监护
- Author:
Guangzhao HE
;
Chengliang ZHANG
- Publication Type:Journal Article
- Keywords:
Pemetrexed;
Renal insufficiency;
Cancer,lung;
Pharmaceutical care
- From:
Herald of Medicine
2016;35(8):839-843
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the pharmaceutical care approaches for patients with lung cancer complicated with renal insufficiency receiving pemetrexed chemotherapy. Methods An elderly patient with lung cancer complicated with renal insufficiency receiving pemetrexed chemotherapy faced inevitable safety risks.Clinical pharmacists considered it as an intervention point, and provided individual pharmaceutical care. Results Clinical pharmacists fully assessed the safety risks of the case receiving pemetrexed chemotherapy with clinicians, assisted in improving the therapeutic regimen, and carried out medication education for the patient. No serious adverse drug reactions occurred in the patient, and anti-tumor efficacy was obtained. Conclusion For patients of lung cancer complicated with renal insufficiency receiving pemetrexed chemotherapy, clinical pharmacists should focus on creatinine clearance rate, and decide whether the combined use of platinum anti-tumor drugs, non steroidal anti-inflammatory drugs and zoledronic acid can be adopted, and follow-up on adverse drug reactions and anti-tumor efficacy.
