Comparison of Epidural Analgesia Effect Between Morphine and Hydromorphone for Patients after Electrotomy of Prostate
10.3870/j.issn.1004-0781.2016.08.014
- VernacularTitle:盐酸吗啡和盐酸氢吗啡酮用于前列腺电切术后硬膜外镇痛效果的比较
- Author:
Leyun ZHAN
;
Zhongyuan XIA
;
Lei ZHANG
;
Bo ZHAO
;
Yang WU
;
Jiabao HOU
- Publication Type:Journal Article
- Keywords:
Hydromorphone,hydrochloride;
Morphine,hydrochloride;
Analgesia;
Transurethral resection,prostate
- From:
Herald of Medicine
2016;35(8):858-860
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe analgesia effect of morphine hydrochloride and hydromorphone hydrochloride in patients after transurethral resection of prostate. Methods Patients after transurethral resection of the prostate (TURP) were randomly divided into 2 groups, morphine hydrochloride group (n=45) and hydromorphone hydrochloride group (n=47). Analgesia, sedation efficacy and adverse reactions were evaluated at 6 and 24 h after they received epidural postoperative analgesia by using VAS score and Ramsay score. Results In 6 h, hydromorphone hydrochloride group had a better pain tolerance and feeling than morphine hydrochloride group (P<0.05) [(2.9±0.3) score vs.(1.3±0.2) score, (2.4±0.3) score vs. (0.9±0.2) score].However, in 6-12 h, the results were on the contrary (P<0.05) [(3.4±0.3) score vs.(5.4±0.3) score, (3.3±0.2) score vs. (5.7±0.4) score].After 24 h, there was no difference between the two groups (P>0.05).There were no differences in adverse reactions between the two groups ( P>0. 05 ) . Conclusion Hydromorphone has a better effect than morphine in epidural analgesia in 6 h.
