Effects of Purple Sweet Potato Flavonoids in Extracts with Different Polarity on IR-HepG2 Cells
- VernacularTitle:紫心甘薯黄酮不同极性提取液对 IR-HepG2细胞的作用
- Author:
Li NAN
;
Yafang LI
;
Chong ZHANG
;
Jingchao SHENTU
- Publication Type:Journal Article
- Keywords:
Purple sweet potato flavonoids;
Insulin resistance;
HepG2 cells
- From:
China Pharmacist
2016;19(7):1239-1241
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of purple sweet potato flavonoids (PSPF)in the extracts with different polarity on the insulin resistant HepG2 (IR-HepG2) cells.Methods: PSPF in the extracts with different polarity was used to intervene the IR-HepG2 model, and the remaining glucose concentration in the IR-HepG2 group and PSPF intervention groups was compared .Results:The remaining glucose concentration in PSPF intervention group , PSPF with chloroform as the extracting solvent at high , medium and low dose of PSPF , and PSPF with butanol as the extracting solvent at high and medium dose of PSPF was obviously lower than that in the IR-HepG2 group(P<0.05).Conclusion:PSPF, the chloroform extract of PSPF and the butanol extract of PSPF can enhance the consumption of glucose in IR-HepG2 cells.
