Study on the HPLC Fingerprint Chromatogram of Cuochuang Xiaoyan Lotion
- VernacularTitle:痤疮消炎洗剂 HPLC指纹图谱研究
- Author:
Jiangping ZHENG
;
Youlin ZHANG
;
Liangyong HUANG
- Publication Type:Journal Article
- Keywords:
Cuochuang Xiaoyan lotion;
HPLC;
Fingerprints;
Quality control
- From:
China Pharmacist
2016;19(7):1276-1279
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To prepare Cuochuang Xiaoyan lotion and establish HPLC fingerprint chromatogram for the quality control . Methods:The separation was performed on a Waters XTerra MS C 18column(250 mm ×4.6 mm, 5μm).The mobile phase consisted of acetonitrile-0.2%phosphoric acid with gradient elution at a flow rate of 1.0 ml· min-1 , the eluent was monitored by a UV detector at 277 nm, and the column temperature was at 30℃.Results: There were sixteen common peaks for the sample , and among them, three ones were identified as baicalin , linarin and rhein , respectively .Conclusion:The repeatability and information of chromatogram peaks of the method are satisfied , which can provide credible quality control method for Cuochuang Xiaoyan lotion .
