Participation of Clinical Pharmacist in the Individualized Drug Treatment for One Case of Overweight Children with Osteosarcoma
- VernacularTitle:临床药师参与1例骨肉瘤超重患儿个体化药物治疗方案的制定
- Author:
Shangwei GUAN
;
Dongyuan WU
;
Mei DONG
- Publication Type:Journal Article
- Keywords:
Osteosarcoma;
Special population;
Body surface area;
Calculation formula;
Individualized drug therapy
- From:
China Pharmacist
2016;19(7):1337-1339
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the role of clinical pharmacists in the development of individualized drug treatment regimens for the osteosarcoma children with irregular body weight .Methods:Clinical pharmacists involved in the calculation of body weight surface area increased to that of adult for one case of osteosarcoma child during the chemotherapy , comparatively analyzed the suitable calcula-tion formula of surface area for the children in our country and helped clinicians make accurate dose of chemotherapy drugs .Mean-while, according to the pathological and physiological characteristics of the child , clinical pharmacist also provided advice on adjuvant drug use such as antiemetic regimen etc .Results:Physicians adopted the suggestions of clinical pharmacists and the chemotherapy was successfully completed .Overdose adverse reactions were avoided without the use of foreign general calculation formula of body surface area for the overweight child , and inadequate dose was also avoided for the conservative treatment , which could lower the risk of re-duced potential anticancer efficacy .Conclusion:Clinical pharmacists can help doctors perform safer and more effective drug treatment program and reduce adverse drug reactions in the treatment of special patients through participation in the development of individualized medication for cancer children to obtain maximum profit .