Research Progress in Antitumor Activity of Dandelion
- VernacularTitle:蒲公英抗肿瘤活性的研究进展
- Author:
Fuliang XIONG
;
Shanshan WU
;
Xinyuan LI
;
Xueqiong ZHANG
- Publication Type:Journal Article
- Keywords:
Dandelion;
Extracts;
Antitumor;
Progress
- From:
China Pharmacist
2016;19(7):1363-1366
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the research advance in antitumor activity of dandelion in recent 5 years.Methods:The lit-eratures on the antitumor activity of various extracts of dandelion in recent 5 years were collected , including the effective components such as polysaccharide , triterpenes , phytosterols , flavonoids and organic acids etc .Results:Dandelion showed antitumor activity .The polysaccharide ingredients could effectively prevent the proliferation of pancreatic cancer PANC -1 cells, lupeol could reduce the activity of breast cancer MCF-7 cells, and beta sitosterol could induce the apoptosis of human cervical cancer Hela cells .Conclusion:Dande-lion is effective in the treatment of pancreatic cancer , breast cancer and cervical cance etc .The antitumor activity of the other active in-gredients in dandelion needs further research in order to provide complete theoretical and experimental evidence for the potential appli -cation as antitumor medicine in clinics .
