Effect of Xingnaojing Injection Combined with Conventional Therapy for Patients with Severe Traumatic Brain Injury
- VernacularTitle:醒脑静注射液联合常规治疗重度颅脑损伤患者效果观察
- Author:
Xiang ZHOU
;
Hongyan HUI
;
Baozhe JIN
- Publication Type:Journal Article
- Keywords:
Xingnaojing injection;
Severe traumatic brain injury;
Clinical effect
- From:
China Pharmacist
2016;19(7):1302-1304
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of Xingnaojing injection in the treatment of severe traumatic brain injury .Methods:From August 2013 to December 2014 , 110 patients with severe traumatic brain injury were randomly divided into the control group and the research group with 55 ones in each .The control group was treated with the conventional treatment , including removal of intracrani-al hematoma, bone disc decompression according to surgical indications , anti-infection, dehydration intracranial pressure reduction and nutritional support treatment .The research group was treated with Xingnaojing injection additionally .After the one-week, two-week and 4-week treatment , the GCS score of the two groups were compared .The rate of lung infection and stress ulcer in 4 weeks were com-pared.The clinical outcome of the two groups after the 4-week treatment was also evaluated .Results:The GCS score of the research group was higher than that of the control group after the 2-and 4-week treatment (P<0.05).There was no significant difference in the incidence of stress ulcer between the two groups , while the incidence of pulmonary infection in the research group was lower than that in the control group (P<0.05).The total effective rate of clinical prognosis in the research group (90.9%) was significantly higher than that in the control group (72.7%, P<0.05).Conclusion:Xingnaojing injection combined with the conventional treatment for the patients with severe traumatic brain injury can decrease the clinical complications and improve the clinical symptoms of patients , which is worthy of clinical promotion .
