Application and Rationality Evaluation of Proton Pump Inhibitors Used in Patients with Cirrhosis or Hepa-titis in One Hospital
- VernacularTitle:某院肝炎或肝硬化患者质子泵抑制药应用合理性评价
- Author:
Zhouye SONG
;
Tao YIN
;
Feng YU
;
Ying ZHU
;
Ping WANG
- Publication Type:Journal Article
- Keywords:
Proton pump inhibitor;
Hepatitis;
Cirrhosis;
Rational drug use
- From:
China Pharmacist
2016;19(7):1342-1344
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the use of proton pump inhibitors ( PPIs) in the patients with cirrhosis or hepatitis in one hospital and evaluate the use rationality .Methods:A retrospective study was carried out on 211 patients with the diagnosis of hepatitis or cirrhosis in the infectious disease ward between 2013 and 2014 , and the use rationality of PPIs was evaluated .Results: A total of 211 cases were inspected, and among them, 192 ones were treated with PPIs (91%) with 62 ones treated with PPIs irrationally, which accounted for 29.3%of the total cases.The main irrational use of PPIs was long treatment course (24.5%), inadequate prophylaxis indications (5.7%) and purposeless use (2.6%).Conclusion: Irrational use of PPI is common in hepatitis or cirrhosis patients . Clinical pharmacists should strengthen pharmaceutical care to improve the rational drug use .
