Risk factors for poor prognosis of severe adenovirus pneumonia in children
10.3969/j.issn.1671-9638.2016.08.012
- VernacularTitle:重度腺病毒肺炎患儿预后不良相关危险因素
- Author:
Zhenzhen WANG
;
Wenlong FU
;
Helin LIU
- Publication Type:Journal Article
- Keywords:
child;
severe;
adenovirus pneumonia;
poor prognosis;
risk factor
- From:
Chinese Journal of Infection Control
2016;15(8):587-591
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the risk factors for poor prognosis of severe adenovirus pneumonia (SAP)in children,and provide guidance for clinical diagnosis and prognosis.Methods Clinical data of 91 hospitalized children who diagnosed with SAP in Chongqing Children’s Hospital of Chongqing Medical University between January 2012 and January 2014 were analyzed retrospectively.Results Of 91 SAP children,23 (25.27%)had poor prognosis. Univariate analysis showed that risk factors for poor prognosis of SAP were age of onset,congenital heart disease and other serious underlying diseases,mechanical ventilation therapy,acute respiratory distress syndrome (ARDS), atelectasis and other serious radiological changes,and emergence of two and more extra-pulmonary complications (all P <0.05).Multivariate regression analysis showed that congenital heart disease and other serious underlying diseases,and emergence of two and more extra-pulmonary complications were independent risk factors for poor prognosis of SAP (all P <0.05).Conclusion Congenital heart disease and other serious underlying diseases,emer-gence of two and more extra-pulmonary complications are independent risk factors for poor prognosis of SAP,active intervention should be conducted during the process of clinical diagnosis and treatment,so as to improve the prognosis.