Biocompatibility of Sextant minimally invasive pedicle screw fixation for osteoporotic vertebral fractures in the elderly
10.3969/j.issn.2095-4344.2016.31.006
- VernacularTitle:Sextant微创椎弓根螺钉内固定修复老年骨质疏松性脊柱骨折的生物相容性
- Author:
Jianjun WU
- Publication Type:Journal Article
- Keywords:
Spinal Fractures;
Osteoporosis;
Internal Fixators;
Tissue Engineering
- From:
Chinese Journal of Tissue Engineering Research
2016;20(31):4603-4609
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Pedicle screw internal fixation is a commonly used method to treat osteoporotic fracture. Internal fixation can effectively reconstruct vertebral body height, restore physiological curvature, and maintain good spinal stability. OBJECTIVE:To investigate the biocompatibility of minimal y invasive percutaneous pedicle screw (Sextant) fixation in the treatment of elderly patients with osteoporotic vertebral fractures. METHODS:A total of 71 cases of senile osteoporotic vertebral fractures were given minimal y invasive percutaneous pedicle screw (Sextant) fixation for treatment. The C-arm X-ray machine was used to accurately locate the fracture vertebral body in different patients, and the corresponding surface was marked. In order to separate the subcutaneous tissue and fascia layer, the internal fixation with Sextant screw was used. 12 months after operation, the fixator was removed. The patients were fol owed up for 12 months, complications and tissues surrounding the fixator were observed. At 1, 3, 6, and 12 months after treatment, changes in Cobb angle, visual analogue scale score and Oswestry disability index were observed. RESULTS AND CONCLUSION:(1) The average operation time was 90.25 minutes;intraoperative blood loss was 85.15 mL. (2) At different time points after treatment, Cobb angle, visual analogue scale score and Oswestry disability index of the patients were significantly decreased at 1 month after treatment, and maintained stable from then on. Cobb angle, visual analogue scale score and Oswestry disability index were significantly less at 1, 3, 6 and 12 months after treatment compared with that before treatment (P<0.05). There was no significant difference in each indicator at different time points after treatment (P>0.05). (3) Two patients affected wound infection, and were cured after symptomatic treatment. No complications such as thrombosis appeared. During removal of the screw, surrounding tissues were observed. There was no inflammatory hyperplasia of soft tissue around the fixator. No fibrous tissue or black wal was found. (4) These results confirm that Sextant minimal y invasive pedicle screw internal fixation in elderly patients with osteoporotic vertebral fractures can obtain satisfactory therapeutic effect, and has good biocompatibility.