Recent progress in the mechanism of estrogen on osteoclasts
10.11958/20160070
- VernacularTitle:雌激素对破骨细胞作用机制研究进展
- Author:
Xiaolei SUN
;
Zhihu ZHAO
;
Xinlong MA
- Publication Type:Journal Article
- Keywords:
estrogens;
osteoclasts;
osteporosis;
osteoporosis;
review
- From:
Tianjin Medical Journal
2016;44(7):925-928
- CountryChina
- Language:Chinese
-
Abstract:
Estrogen is involved in the process of postmenopausal osteoporosis, and the main functional cells are osteoclasts. However, the mechanism of estrogen on the osteoclasts is not yet fully understood. Here we demonstrate the effects of estrogen on osteoclasts in three aspects: morphology and structure, apoptosis of osteoclasts and differentiation of preosteoclasts, which give an overall explanation for effects of estrogen on osteoclasts.
