Pathophysiologic mechanisms and therapeutic methods of sarcopenia in cancer cachexia
10.3760/cma.j.issn.1674-635X.2016.03.012
- VernacularTitle:癌性恶病质肌肉减少的病理生理机制和治疗方法
- Author:
Lixin WANG
;
Yanbing ZHOU
- Publication Type:Journal Article
- Keywords:
Cancer cachexia;
Sarcopenia;
Pathophysiologic mechanisms;
Therapeutic methods
- From:
Chinese Journal of Clinical Nutrition
2016;24(3):179-185
- CountryChina
- Language:Chinese
-
Abstract:
Sarcopenia is a major clinical characteristic of cancer cachexia .The main pathophysiologic mechanism of sarcopenia related to cancer cachexia is abnormality between anabolic and catabolic pathways of muscle mediated by chronic inflammation .The major treatments for sarcopenia in cancer cachexia currently in-clude hormone therapy , nutrition support , exercise therapy , and other medications , which could not effectively prevent muscle loss or enhance muscle function .Better understanding of the pathogenetic processes of cancer cachexia-related sarcopenia may help in finding targets for an effective therapy .
