Correlation between retraction phenomenon on the coronal planes and biological behaviors of breast cancer
10.3760/cma.j.issn.1004-4477.2016.06.009
- VernacularTitle:乳腺癌冠状面汇聚征和生物学行为指标间的相关性研究
- Author:
Fengyang ZHENG
;
Beijian HUANG
;
Lixia YAN
;
Xi WANG
;
Jun YANG
;
Haiyun SHEN
;
Wei YUAN
- Publication Type:Journal Article
- Keywords:
Ultrasonography three-dimensional Breast neoplasms Retraction phenomenon Automated breast volume scanner
- From:Chinese Journal of Ultrasonography
2016;25(6):496-501
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between retraction phenomenon on the coronal planes obtained by an automated breast volume scanner ABVS and biological behaviors of breast cancer Methods Two hundred and eighty-eight female patients with 293 pathologically proven breast cancers were included in this study All of them underwent ABVS examinations before surgery Retraction phenomenon on the coronal planes was evaluated retrospectively Correlation between retraction phenomenon and hormone receptor HR human epidermal growth factor receptor 2 HER-2 Ki-67 molecular subtypes histologic type histologic grade lymph node status lesion size and patient age were evaluated by univariate logistic regression analysis Above significant variables were then enrolled in multivariate logistic regression analysis to select independent risk factors for retraction phenomenon Results By univariate logistic regression analysis Luminal A subtype odds radio OR =8 395 P <0 001 HR positive OR=4 876 P <0 001 HER-2 negative OR = 4 407 P < 0 001 lower expression of Ki-67 OR = 3 716 P <0 001 lower grade OR=3 574 P <0 001 lymph node invasion OR=2 053 P =0 004 and smaller lesion OR=1 762 P =0 033 were risk factors for retraction phenomenon while histologic type P =0 3 1 8 and patient age P = 0 612 were not By multivariate logistic regression analysis Luminal A subtype OR=9 877 P <0 001 lower grade OR=3 573 P <0 001 and lymph node invasion OR=2 730 P = 0 004 were independent risk factors for retraction phenomenon among which Luminal A subtype was the strongest one Conclusions Retraction phenomenon on the coronal planes obtained by ABVS is closely related with Luminal A subtype and may be an imaging feature of less aggressive behaviors of breast cancer.
