Effects of Pharmacogenomics on Individualized Drug Treatment
- VernacularTitle:药物基因组学对个体化药物治疗的影响
- Author:
Kexin ZHAO
;
Rui SHI
;
Cen LI
;
Qian WANG
;
Shengxiang WANG
;
Yanping REN
;
Rui ZHANG
- Publication Type:Journal Article
- Keywords:
Pharmacogenomics;
Single nucleotide polymorphism;
Drug metabolic enzyme;
Drug transporter;
Drug target
- From:
China Pharmacist
2016;19(6):1162-1166
- CountryChina
- Language:Chinese
-
Abstract:
Pharmacogenomics is a discipline studying the influence of genetic differences on drug effectiveness .It promises to op-timize the effect of medicine and reduce side effects .It is one of the most effective ways to predict the drug reaction in human body by using pharmacogenomics , which can achieve the goal of precision medicine .With the rapid development of the genetical test technolo-gies, the in vitro individual genome testing projects with the properties of high throughput , and measurable and low cost are better to be applied in medical practice and guiding for making individualized medicine plan .The study elucidated the progress in single nucleotide polymorphism and its clinical application , and focused on the strategic effects of pharmacogenomics on individualized treatment and gene diversity for guiding medicine .
