Overview on an Originate AngiotensinⅡReceptor-Neprilysin Inhibitor with Double Effect:Sacubitril/Val-sartan
- VernacularTitle:首创的双效血管紧张素受体-脑啡肽酶抑制药沙库必曲／缬沙坦概述
- Author:
Xin LI
;
Bingtuan LEI
;
Chao LI
- Publication Type:Journal Article
- Keywords:
Neprilysin inhibitor;
Angiotensin Ⅱreceptor inhibitor;
Heart failure;
Sacubitril/Valsartan
- From:
China Pharmacist
2016;19(6):1167-1169
- CountryChina
- Language:Chinese
-
Abstract:
An originate angiotensin Ⅱreceptor-neprilysin inhibitor sacubitril/valsartan with double effect and a new active mode can not only promote the protection of heart and neuroendocrine system , but also inhibit renin-angiotensin-aldosterone system .Sacubi-tril/valsartan is the first and only one conformed by clinical trials with better efficacy when compared with standard therapy drug enala -pril, and its safety is higher as well .Sacubitril-valsartan represents a promising new treatment option for heart failure patients with low-ered risk of cardiovascular death and hospitalization for heart failure .
