Investigation on Stability of TPN Solution Containing Vitamin C
- VernacularTitle:含维生素 C肠外营养液的稳定性考察
- Author:
Ying WANG
;
Hua WANG
;
Qian YU
- Publication Type:Journal Article
- Keywords:
Total parenteral nutrition;
Stability;
Vitamin C;
HPLC
- From:
China Pharmacist
2016;19(6):1203-1206
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the stability of total parenteral nutrition ( TPN) solution used in our hospital .Methods:The ap-pearance and pH of the compatibility solution were observed and the content of vitamin C was determined in 8 h after the compatibility . Results:The content of vitamin C in compound amino acid solution was decreased with the time , and the solution turned yellow in 4 h and the content of vitamin C was decreased by 10%, while no notable change in pH value was shown .The solution without compound amino acid was stable in 6 h.Conclusion:Vitamin C injection mixed with TNP solution containing compound amino acid is not recom-mended, and vitamin C should be used alone .
