Analysis on drug resistance in 404 strains of Acinetobacter Baumannii isolated from Neurosurgery wards
10.3969/j.issn.1673-4130.2016.13.006
- VernacularTitle:神经外科病房404株鲍曼不动杆菌的耐药性分析
- Author:
Li GUO
;
Xiaolan GUO
;
Jiankang DENG
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
drug resistance;
antibacterial agents;
neurosurgery department wards
- From:
International Journal of Laboratory Medicine
2016;37(13):1762-1764
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the specimen source and drug resistance in the strains of Acinetobacter baumannii isolated from the submitted samples in the neurosurgery wards of our hospital during 2011-2014 in order to provide the reference for clini‐cal treatment and nosocomial infection control .Methods A retrospective analysis was performed on the clinical data of clinical dis‐tribution and antibacterial drugs sensitivity in 404 non‐repeated strains of Acinetobacter baumannii isolated from the samples of neurosurgical patients .Results The mainly specimen source of Acinetobacter baumannii isolated from neurosurgical patients was sputum and cerebrospinal fluid ,accounting for 89 .1% and 7 .9% respectively .Acinetobacter baumannii isolates showed the lowest resistance rates to minocycline and cefoperazone/sulbactam (28 .6% and 31 .8% respectively) .The resistance rates to imipenem and meropenem were 79 .4% and 83 .2% respectively ;the resistance rate to other antibacterial drugs exceeded 69 .0% .Conclusion Acinetobacter baumanii strains isolated from the neurosurgery department have higher resistance rates to many kinds of antibacteri‐al agents ,minocycline and cefoperazone/sulbactam still has good in vitro antibacterial activity against Acinetobacter baumanii .Clinic should strengthen the management of antibacterial agents ,increases the rate of drug susceptibility test and rationally uses the anti‐bacterial drugs .
