Nucleic acid aptamer for caner therapeutics and diagnostics
10.3760/cma.j.issn.1673-422X.2016.07.009
- VernacularTitle:核酸适配体分子探针在肿瘤诊断和治疗中的研究进展
- Author:
Jianwei LIANG
;
Ruping YAN
;
Jiansong WANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Aptamers,nucleotide;
Molecular diagnostic techniques;
Therapy
- From:
Journal of International Oncology
2016;43(7):519-522
- CountryChina
- Language:Chinese
-
Abstract:
Nucleic acid aptamer is the systematic evolution of ligands by exponential enrichment syn-thesized in vitro screening technology resulting single-stranded oligonucleotides (DNA or RNA),by folding into unique spatial structure specific recognition binding target molecules.Aptamers function is similar to the anti-bodies but more specifically,as novel molecular probes for the field of cancer therapeutics and diagnostics.