Progress of molecular biology and treatment for triple negative breast cancer
10.3760/cma.j.issn.1673-422X.2016.07.011
- VernacularTitle:三阴性乳腺癌的分子生物学及治疗进展
- Author:
Junjie LIU
;
Jun QIAN
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Molecular biology;
Genes;
Therapy
- From:
Journal of International Oncology
2016;43(7):526-528
- CountryChina
- Language:Chinese
-
Abstract:
Triple negative breast cancer (TNBC)is difficult to benefit from endocrine therapy or tras-tuzumab targeted drug therapy.Biological overexpression of breast cancer susceptibility gene 1,p53 gene,vas-cular endothelial growth factor and microRNA suggests that TNBC is easy to metastasis and recurrence and has a poor prognosis.Exploring the molecular subtypes of TNBC,setting out the treatment plan for subtypes and finding the corresponding monoclonal antibody targets are the research direction of TNBC in the future.
