The clinical features of neuro-Behcet disease with epileptic seizure as the primary symptom
10.3760/cma.j.jssn.1673-4904.2016.07.018
- VernacularTitle:以癫痫为首发表现的神经白塞病
- Author:
Shujiang ZHANG
;
Zuoxiao LI
- Publication Type:Journal Article
- Keywords:
Magnetic resonance imaging;
Epilepsy
- From:
Chinese Journal of Postgraduates of Medicine
2016;39(7):635-638
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical features and image characteristic of neuro-Behcet disease with epileptic seizure as the primary symptom. Methods The data of 4 patients with neuro-Behcet disease with epileptic seizure as the first symptom were collected and retrospectively analyzed. Results One patient had recurrent joint pain in the department of dermatology, and 1 patient had blurred vision in the department of ophthalmology. They were shifted to department of neurology because of epileptic seizure. Head CT of four patients were normal. There were abnormal signal in brainstem in 2 cases, and in the other 2 cases, there were symmetry abnormal signals in periventricle, centrum semiovale. The abnormal signal was low in T1 weighted image and high in T2 weighted image, flair, diffuse weighing imaging , but there were no abnormal signals in cortex in these 4 cases. In CSF examination, 3 patients′cell number was high, 1 patient′s cell number was normal, 2 patients′protein levels were high, and the other 2 patients′protein levels were normal. One patient had spike wave and sharp wave in video-EEG, and the other 3 patients were normal. Conclusions Epileptic seizure is rare in neuro-Behcet disease, and CT and MRI is frequently-used in diagnosing nervous system disease. There are no abnormal signals in cortex, but there are generalized tonic-clonic seizure, which may relate with the abnormal discharge of cortex.
