Research progress of transforming growth factor beta 1 in the treatment of chronic viral hepatitis B
10.3760/cma.j.jssn.1673-4904.2016.07.028
- VernacularTitle:转化生长因子β1在慢性乙型病毒性肝炎抗病毒治疗中的研究进展
- Author:
Donglan CHEN
;
Weiqiang ZHENG
- Publication Type:Journal Article
- Keywords:
Transforming growth factor beta1;
Virus replication;
Immunomodulation;
Hepatitis B,chronic;
Antiviral agents
- From:
Chinese Journal of Postgraduates of Medicine
2016;39(7):659-662
- CountryChina
- Language:Chinese
-
Abstract:
Transforming growth factor beta1 (TGF-β1) is the product and adjusting factor of the hepatocyte immune process when Hepatitis B virus (HBV) invades. There was a correlation among the level of TGF-β1, immune cell cytokines and HBV replication during antiviral therapy. It has an important clinical significance for the researchers to investigate dynamic change of TGF-β1 in chronicviral hepatitis type B (CHB) immunological response and antiviral treatment.