Glucose level of oral glucose tolerance test is associated with the occurrence of large for gestational age infants

VernacularTitle:妊娠期妇女糖耐量试验血糖水平对大于胎龄儿的影响
Author: Feifei LIU ; Bo BAN ; Dongmei MAN ; Ping LI ; Mingming HE
Publication Type:Journal Article
Keywords: _ Gestational diabetes mellitus; Oral glucose tolerance test; Large for gestational age
From: Chinese Journal of Endocrinology and Metabolism 2016;32(6):480-482
CountryChina
Language:Chinese
Abstract: To explore the influence of glucose level of 75 g oral glucose tolerance test ( OGTT ) druing pregnancy on delivery of large for gestational age infants. This research selected 790 cases of patients diagnosed as gestational diabetes mellitus( GDM) , 478 cases of pregnant women diagnosed as normal glucose tolerance( NGT) from Affiliated Hospital of Jining Medical University in 2014 and followed up until they delivered. Single live births were selected, risk factors which had influence on offsprings, birth weight were analysed. GDM group had significantly higher rate of delivering large for gestational age(LGA)infants than that of NGT group(47. 30% vs 31. 30%, P<0. 05). Adjusting for confounding factors, it suggested that 2 h plasma glucose level of 75 g OGTT was an independent risk factor for the delivery of LGA infants, and 1 mmol/L glucose increment in 75 g OGTT 2 h plasma glucose level, mayincreasetheriskofLGAby29%(OR=1.29,95%CI1.05-1.58,P=0.02). The2hplasmaglucoselevelof75 g OGTT is an independent risk factor for delivery of LGA infants.