The relationship between the waist circumference level and the non-alcoholic fatty liver disease of the Kailuan Group population
10.3760/cma.j.issn.1000-6699.2016.06.010
- VernacularTitle:开滦集团人群腰围水平与非酒精性脂肪性肝病的相关性研究
- Author:
Liying LIU
;
Junling ZHANG
;
Shuang LIU
;
Li ZHANG
;
Xing LIU
;
Jie LIANG
;
Xiurong LIU
- Publication Type:Journal Article
- Keywords:
_ Waist circumference;
Non-alcoholic fatty liver disease;
Relationship
- From:
Chinese Journal of Endocrinology and Metabolism
2016;32(6):483-487
- CountryChina
- Language:Chinese
-
Abstract:
_ Objective_ To explore the relationship between the waist circumference ( WC) level and the non-alcoholic fatty liver disease ( NAFLD) in the Kailuan Group population. Methods A total of 7 896 individuals were selected as observed subjects from the Kailuan Group in 2011-2012 health physical examination. A questionnaire survey, blood biochemical, and abdominal ultrasound examination were finished by trained medical staff. According to the WC measurement and its quartile in the health examination, the observed subjects were divided into four groups (first, second, third, and forth quartile groups). Multivariate logistic regression analysis was used to analyze the relationship between the WC level and the NAFLD. Results ( 1 ) The detection rate of NAFLD in central obesity groupwashigherthanthatinnon-obesitygroup(67.1% vs27.9%,P<0.01). AlongwithincreasingWClevelinthe 4 quartile groups, the incidences of NAFLD were progressively increased, being 7. 1%, 23. 4%, 33. 4%, and 36. 1%, respectively. In the total population, the detection rates were 18. 8%, 42. 5%, 62. 0%, and 76. 1% in males;5. 4%, 24. 1%, 44. 7% and 62. 9% in females. (2)Multivariate logistic regression analysis showed that WC is an independent risk factor after adjusting age, gender, and other risk factors, the OR value being 1. 08. It was also noticed that compared with the first quartile group, the second, third, and forth quartile groups had increased risk of NAFLD after adjusting above factors in different genders, with the OR values being 2. 74, 6. 59, and 11. 15 in males, while 2. 61, 5. 03, and 3. 67 in females, respectively. Conclusion WC was an independent risk factor for NAFLD;the incidence of NAFLD increased with increasing WC level in the Kailuan Group population.
