Research progression of exosome in breast cancer
10.3760/cma.j.issn.1009-9158.2016.06.017
- VernacularTitle:外泌体在乳腺癌中的研究进展
- Author:
Yan ZHANG
;
Xianjuan SHEN
;
Shaoqing JU
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Exosomes;
Tumor microenvironment;
Drug resistance,neoplasm;
Tumor markers,biological
- From:
Chinese Journal of Laboratory Medicine
2016;39(6):466-469
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are small (30 -100 nm) membrane vesicles secreted by various cell types , they mediate cell-to-cell communication by transferring mRNAs , miRNAs, and proteins.As a hotspot in the research of oncology , exosomes have potential values in the research of development , diagnosis and treatment of cancer. This paper briefly reviews the relationship between breast cancer microenvironment , drug resistance and exosomes and its progress in breast cancer diagnosis and treatment , in order to propose new diagnostic and therapeutic strategies .
