Nutritional status during radiotherapy in different age patients with esophageal cancer
10.3760/cma.j.issn.1674-0815.2016.03.012
- VernacularTitle:不同年龄段食管癌患者放疗期体格及营养状况分析
- Author:
Yingjun YE
;
Shuping XIE
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Radiotherapy;
Nutrition assessment
- From:
Chinese Journal of Health Management
2016;10(3):218-222
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the nutritional status in different age patients with esophageal cancer during radiotherapy. Methods Ninety nine patients with esophageal carcinoma accepted radiotherapy in Zhejiang Cancer Hospital from June 2012 to August 2013 were enrolled. Patients were divided into two groups by their age: the younger age<60 years; and the older age ≥60 years. Nutritional status was measured weekly during radiotherapy, and European Nutritional Risk Screening (NRS) 2002 were used to evaluate the risk of malnutrition. Results The malnutritional incidence during radiotherapy was 23.5%-29.4% and 33.8%-49.2% in the younger group and the older group, respectively. Compared with baseline nutritional parameters, triceps skinfold thickness (TSF) of the<60 years group started to differ at the first week after the start of radiotherapy (first week to the sixth week:9.14±8.67;7.80±2.90;7.62±2.83;7.56± 2.79;7.90±2.91;7.36±2.67, respectively, all P<0.01);compared with baseline nutritional parameters(2.09± 1.28), ≥60 years group started to differ at the second week (2.34 ± 1.24, P<0.05) after the start of radiotherapy for NRS2002 the third week, 2.49 ± 1.24, P=0.016;the fourth week, 2.51 ± 1.30;P=0.013, the fifth week, 2.55 ± 1.29, P=0.006; the sixth week, 2.57 ± 1.26, P=0.004. There was no significant difference between each time point for TSF in>60 years group (P>0.05). No significant difference was found for body mass index (BMI), arm circumference (AC), arm muscle circumference (AMC) in each group (P>0.05). Conclusion The elderly patients with esophageal cancer had significantly increased risk of malnutrition and decreased nutritional status than the younger patients during radiotherapy. Early start of nutrition interventions in the elderly patients may be benefitted.
