Clinical features of patients with polycystic ovary syndrome with different SHBG levels
10.3969/j.issn.1006-5725.2016.12.022
- VernacularTitle:不同性激素结合球蛋白水平对多囊卵巢综合征患者的影响
- Author:
Yinghua LIU
;
Lihui HOU
;
Fang XU
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Polycystic ovarian syndrome;
Sex hormone-binding globulin;
Insulin resistance
- From:
The Journal of Practical Medicine
2016;32(12):1969-1971
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of SHBG in PCOS. Methods Three hundred and ten PCOS patients were divided into the low-SHBG group , the normal-SHBG group , and 95 healthy women were enrolled in the healthy control group. Results (1) In the low SHBG group, the incidences of IR and MS were higher than those in the the normal SHBG group and the healthy control group (P < 0.05); (2) In the low SHBG group, DHEAS was significantly higher than that in the normal SHBG group (P < 0.05); (3) In the low SHBG group, FINS, HOMA-IR, TG, TC/HDL, TG/HDL, LDL/HDL were significantly higher than those in the normal SHBG group and the healthy control group , but HDL was significantly lower than that in the normal SHBG group (P < 0.05); (4) SHBG was positively correlated with HDL, but was negatively correlated with FPG, FINS, HOMA-IR, TG, TC/HDL, TG/HDL, LDL/HDL. Conclusions Uner the low SHBG level, PCOS patients have high levels of DHEAS, and SHBG may be a risk factor for MS, IR and dislipidemia.
