Clinical and imaging characteristics in cryptogenic ischaemic stroke with right-to-left shunt
10.3969/j.issn.1002-0152.2016.05.003
- VernacularTitle:伴右向左分流的隐源性缺血性卒中的临床和影像学特征
- Author:
Shujin TANG
;
Yuhua FAN
;
Hongbing CHEN
;
Wenjin SHANG
;
Jingjing LI
;
Jinsheng ZENG
- Publication Type:Journal Article
- Keywords:
Cryptogenic stroke;
Right-to-left shunt;
Paradoxical embolism;
Imaging characteristics;
Risk factors
- From:
Chinese Journal of Nervous and Mental Diseases
2016;42(5):267-271
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and imaging characteristics in cryptogenic stroke with right-to-left shunt (RLS). Methods Fifty-two patients with cryptogenic ischaemic stroke were included in the study and divided into two groups according to transcranial Doppler (TCD) bubble test: RLS group (twenty-five patients) and non-RLS group (twenty-seven patients). The demographic data, traditional risk factors of stroke and characteristics of le?sion patterns were compared between two subgroups. Results There was no significant difference between the groups in age or sex ratio. The percentage of patients with no risk factors was significantly higher in RLS group than non-RLS group (44%vs. 14.8%, P=0.015). The lesion was more frequently observed in the vertebrobasilar artery territory in RLS group (56%vs. 14.8%, P<0.01). However, there was no other significant difference in lesion patterns, such as infarct size, single/multiple lesions, superficially/deeply located between these two groups(P>0.05). Conclusions Vertebrobasilar Stroke without traditional cerebrovascular risk factors is more likely to be RLS-associated, which requires an advanced TCD bubble test to find the potential cause of stroke.
