Incidence and influence factors of accidental awareness during general anesthesia in selective operation
- VernacularTitle:择期全麻手术患者术中知晓影响因素分析
- Author:
Bingxiao ZHAO
;
Yanqiu AI
;
Feng JIN
;
Long HE
;
Da LI
;
Shuchi ZHANG
- Publication Type:Journal Article
- Keywords:
General anesthesia;
Accidental awareness;
Influence factors
- From:
The Journal of Clinical Anesthesiology
2016;32(6):547-549
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively investigate the incidence of accidental awareness during general anesthesia in selective operation and analyze the influence factors of accidental aware-ness.Methods Patients scheduled for elective surgery requiring general anesthesia with artificial air-way during April 2013-July 2015 were collected.The incidence was obtained from postoperative fol-low-ups.Perioperative data and anesthetic drugs were collected to analyze influence factors. Results A total of 141 294 patients were enrolled.Eighty patients (0.06%)were definitely identified as awareness.Multiple regression analysis showed that awareness during operation was associated with total intravenous anesthesia (OR=5.181,95% CI 3.032-8.853),using laryngeal mask airway (OR=2.478,95% CI 1.544-3.977)and ASA Ⅲ or Ⅳ (OR=9.202,95% CI 5.475-15.466).Pre-medication of midazolam (OR=0.125,95% CI 0.080-0.196)and combination of sevoflurane (OR=0.193,95% CI 0.113-0.330)had lower incidence of awareness during operation.Conclusion Total intravenous anesthesia,using laryngeal mask airway and ASA Ⅲ or Ⅳ are risk factors of accidental awareness during general anesthesia.Premedication of midazolam and combination of sevoflurane may prevent awareness during operation.
