Effect of body temperature for favorable neurological outcome in patients of cardiac arrest
- VernacularTitle:心脏骤停复苏后患者体温对脑功能预后的影响
- Author:
Da HUANG
;
Jianfeng LIANG
;
Xi ZHU
;
Youzhong AN
;
Gang LI
;
Qing LI
;
Yong LUO
;
Dongxin WANG
;
Xueying LI
- Publication Type:Journal Article
- Keywords:
Cardiac arrest;
CPR;
Prognosis;
Hypothermia
- From:
The Journal of Clinical Anesthesiology
2016;32(6):567-572
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the association between body temperature and neurological outcome in post-arrest patients.Methods This was a multicenter,retrospective cohort study.In the period 1990-2011,a total of 184 patients resuscitated from IHCA with ROSC for more than 20 min were included.Data were collected according to Utstein style.The primary endpoint was hospital dis-charge with good neurological function (Cerebral Performance Category,CPC,1-2).Multivariate Lo-gistic regression was performed to determine the association between body temperature and neurologi-cal outcome.Results Among the 184 enrolled patients,37.0% (68/184)survived to hospital dis-charge,19.6% (36/184)survived to discharge with favorable neurological outcome(CPC,1-2).Mul-tivariate Logistic regression revealed that maximal body temperature between 35.5℃ and 38.4℃ was associated with favorable neurological outcomes (OR=8.986,95% CI 1.156-69.882;P =0.036). Conclusion For IHCA patients achieving spontaneous circulation, maximal body temperature between 35.5℃ and 38.4℃ in the initial 24 h following admission to ICU was associated with favora-ble neurological outcome.
