Hydrogen sulfide productivity of mononuclear cells from patients with atrial fibrillation
10.3969/j.issn.1006-5725.2016.12.018
- VernacularTitle:心房颤动患者单个核细胞硫化氢产率的变化
- Author:
Lin HAN
;
Huili SHI
;
Guangzhen ZHONG
;
Lin XU
- Publication Type:Journal Article
- Keywords:
Atrial fibrillation;
Hydrogen sulfide;
Mononuclear cells
- From:
The Journal of Practical Medicine
2016;32(12):1955-1958
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the hydrogen sulfide productivity by mononuclear cells in patients with atrial fibrillation (AF). Methods Mononuclear cells were extracted from peripherial blood of 60 AF patients and 30 healthy controls. Modified methylene blue method was used to evaluate the hydrogen sulfide productivity of mononuclear cells. Results Hydrogen sulfide productivity of mononuclear cells from AF patients was 92.5%higher than that from control [10.63 (8.21~14.37) μmol/(min.g protein) vs 5.52 (4.42~8.50) μmol/(min.g protein)]. Hydrogen sulfide productivity of mononuclear cells was correlated with the left atrial transverse diameter (r = 0.276,P < 0.01), while no significant correlation was found between hydrogen sulfide and left ventricular end-diastolic diameter , left atrial anterior posterior diameter , C-reaction protein etc. Conclusion Hydrogen sulfide productivity of mononuclear cells from AF patients is promoted.
