Observation on perioperative stress reactions and postoperative inflammatory reactions in patients with ;severe pancreatitis treated by minimally invasive surgery and open surgery
10.3969/j.issn.1006-5725.2016.12.031
- VernacularTitle:微创手术与开腹手术治疗重症胰腺炎的围术期应激反应及术后炎性反应
- Author:
Zhong WANG
;
Weidong XU
;
Buwei TENG
- Publication Type:Journal Article
- Keywords:
Severe pancreatitis;
Minimally invasive surgery;
Open surgery;
Stress reaction
- From:
The Journal of Practical Medicine
2016;32(12):1997-1998
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy in patients with severe pancreatitis treated by minimally invasive surgery and open surgery. Methods Seventy-three cases of patients with severe pancreatitis which were treated in our hospital between June 2011 and June 2015 were divided into group A (n = 37) and group B(n =36). Group A were treated by minimally invasive surgery while group B by open surgery. The perioperative stress reactions , postoperative inflammatory reactions , incidence of complications and mortality were compared between the two groups. Results The proportion of patients with perioperative (0+1) level pain in group A (70.3%) was significantly higher than that in group B (44.4%) (P < 0.05). Seventy-two hours after surgery, the CRP, TNF-α and IL-6 in group A were lower than those before surgery and those in group B while APN in group A was higher than that before surgery and that in group B (P < 0.05). The incidence of pulmonary infection and mortality in group A (27.0%, 5.4%) were lower than those in group B (50.0%, 22.2%) (P < 0.05). Conclusions Minimally invasive surgery in the treatment of severe pancreatitis has slight trauma. The postoperative pain is mild and complications are fewer , and the mortality is low.
