Relationship between levels of serum gamma-glutamyltransferase and coronary heart disease in pilots

VernacularTitle:血清γ-谷氨酰转移酶与飞行员冠心病的关系
Author: Na ZHANG ; Chao WU ; Mingyuan LIAO ; Cheng YU ; Jun WANG ; Zhongli MA ; Jianwei TIAN
Publication Type:Journal Article
Keywords: Pilots; Coronary disease; Gamma-glutamyltransferase; Gensini score
From: The Journal of Practical Medicine 2016;32(11):1774-1777
CountryChina
Language:Chinese
Abstract: Objective To investigate the correlation between serum level of gamma-glutamyl transferase (GGT) and coronary heart disease (CHD) in military pilots. Methods Sixty male military pilots hospitalized in Airforce General Hospital having coronary angiography examination(CAG) from March 2005 to May 2015 were involved then were divided into CHD group (n = 24) and control group (n = 36) according to the results of coronary angiography (CAG). The patients with CHD were divided into low score group (Gensini score ≤ 20) and high score group (Gensini score > 20) according to Gensini score. Results There were significant increase of the level of TG, GGT and decrease of the level of HDL-C in CHD group than those in control group(P<0.05);there was no significant difference with the level of GTT between high score group and low score group (P > 0.05); logistic regression analysis showed that serum GGT was an independent risk factor of CHD in military pilots (OR = 1.168, P < 0.01). Conclusion Serum GGT is associated with CHD in military pilots and is the independent risk factor of CHD in the pilots.