Therapeutic Observation of Acupuncture for Oxycodone Hydrochloride-induced Constipation
10.13460/j.issn.1005-0957.2016.07.0827
- VernacularTitle:针刺治疗盐酸羟考酮缓释片所致便秘疗效观察
- Author:
Ruirui SUN
;
Jing WANG
;
Jing CHEN
;
Fengqin WU
- Publication Type:Journal Article
- Keywords:
Acupuncture therapy;
Oxycodone hydrochloride sustained-release tablets;
Constipation;
Lactulose oral solution;
Drug-related side effects and adverse reactions
- From:
Shanghai Journal of Acupuncture and Moxibustion
2016;35(7):827-829
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of acupuncture in treating Oxycodone hydrochloride-induced constipation in cancer pain patients.Method Sixty cancer pain patients with Oxycodone hydrochloride-induced constipation were randomized into a treatment group and a control group, 30 cases in each group. The treatment group was intervened by acupuncture, while the control group was by oral administration of lactulose oral solution. The therapeutic efficacies were compared after 2-week treatment, and the quality of life was evaluated before and after treatment.Result The total effective rate was 90.0% in the treatment group versus 73.3% in the control group, and the difference was statistically significant (P<0.05). The Karnofsky Performance Status (KPS) score was significantly changed in the treatment group after intervention (P<0.05). There was a significant difference in comparing the KPS score between the two groups after treatment (P<0.05).Conclusion Acupuncture can produce a significant efficacy in treating Oxycodone hydrochloride-induced constipation, and also improve the patients’ quality of life.
