A Non-Enzymatic Glucose Sensor Based on Polydopamine/Cu Microparticles Self-assembled Multilayer Films
10.11895/j.issn.0253-3820.150853
- VernacularTitle:基于聚多巴胺/铜微粒自组装多层膜的无酶葡萄糖传感器
- Author:
Mingrong LUO
;
Liangliang WANG
;
Yajing ZHANG
;
Shuang ZHAO
- Publication Type:Journal Article
- Keywords:
Layer-by-layer self-assembly;
Non-enzymatic sensor;
Glucose;
Electrocatalysis;
Dopamine autopolymer
- From:
Chinese Journal of Analytical Chemistry
2016;44(6):882-887
- CountryChina
- Language:Chinese
-
Abstract:
A highly stable multilayer film modified glassy carbon electrode (GCE) containing polydopamine (PDA) and Cu microparticles was fabricated by layer-by-layer self-assembly technique. The fabrication process was based on the self-polymerization of dopamine and electroless deposition of Cu microparticles on PDA coating. The fabrication process of multilayer films was characterized by UV-Vis spectra. The electrochemical performance of GCE / (PDA/ Cu) n modified electrode for glucose detection was investigated by cyclic voltammetry and amperometric current-time curve under alkaline conditions. At detection potential of 0. 35 V, the GCE / ( PDA/ Cu) 4 modified electrode presented a linear range of 0. 5 - 9. 0 mmol/ L with a detection limit of 5. 8 μmol/ L (S / N=3). Moreover, the sensitivity of the modified electrode was tunable by controlling the number of bilayers of the multilayer films. The modified electrode showed highly selective, stable and fast amperometric sensing of glucose. It was applied to determine glucose in human blood serum with satisfactory results.
