Effect and Mechanism of Intestinal Bacteria Flora on Colorectal Cancer
10.3969/j.issn.1008-7125.2016.05.015
- VernacularTitle:肠道菌群在结直肠癌中的作用及其机制
- Author:
Yongtao YANG
;
Changmin QU
;
Lianyong LI
- Publication Type:Journal Article
- Keywords:
Intestinal Bacteria;
Colorectal Neoplasms;
Environmental Factors;
Inflammation;
Gene
- From:
Chinese Journal of Gastroenterology
2016;21(5):315-318
- CountryChina
- Language:Chinese
-
Abstract:
Increasing evidences have shown that intestinal microbiota may contribute to the etiology of colorectal cancer(CRC). Studies have shown some microbial species which can increase the risk of CRC. Intestinal bacteria can promote carcinogenesis by affecting DNA integrity,regulating immune reaction,inducing inflammation,increasing cell proliferation and altering stem cell dynamics. Modulation of intestinal microbiota may become an approach to prevent or treat CRC. This article reviewed the effect and mechanism of intestinal bacteria flora on CRC.
