Clinical analysis of 23 cases of histiocytic necrotizing lymphadenitis presented as fever of unknown origin
10.3760/cma.j.issn.1671-7368.2016.06.014
- VernacularTitle:以不明原因发热为表现的组织细胞坏死性淋巴结炎23例临床分析
- Author:
Wei WANG
;
Xiaochun SHI
- Publication Type:Journal Article
- Keywords:
Histiocytic necrotizing lymphadenitis;
Fever of unknown origin;
Pathological conditions,signs and symptoms
- From:
Chinese Journal of General Practitioners
2016;15(6):463-465
- CountryChina
- Language:Chinese
-
Abstract:
We retrospectively analyzed 23 cases of histiocytic necrotizing lymphadenitis (HNL) admitted to our hospital as fever of unknown origin (FUO).Fever,lymphadenopathy and skin rash were the most common clinical manifestation.The major laboratory features included cytopenia,abnormal liver enzyme and elevated inflammatory markers.Three of the 23 cases were finally diagnosed as infectious disease,5 as autoimmune disease,while the left 15 remained as HNL during the follow-up.Four of the 15 HNL patients resolved spontaneously,while the other 11 relieved by steroid use.Two patients relapsed during the follow-up.HNL was one of the rare causes of FUO.Since it would be accompanied with infectious,autoimmune or malignant diseases,long follow-up is necessary.
