Analysis on Pharmacologic Action Features of Active Ingredients of Single Chinese Herbal Medicine for the Treatment of Fatty Liver Based on Literature
10.3969/j.issn.1005-5304.2016.07.011
- VernacularTitle:基于文献的单味中药有效成分治疗脂肪肝药理作用特点分析
- Author:
Zhou ZHONG
;
Yankun DENG
;
Zhixi HU
;
Qian XU
;
Yongjin LAI
;
Yunbo WEN
- Publication Type:Journal Article
- Keywords:
alcoholic fatty liver;
nonalcoholic fatty liver disease;
Chinese herbal medicine;
pharmacological action
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(7):42-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze pharmacologic action features of single Chinese herbal medicine for the treatment of fatty liver based on literature; To provide references for clinical treatment of fatty liver.Methods Animal research literature about single Chinese herbal medicine for the treatment of fatty liver in CNKI, Wanfang database, and VIP from January 2003 to December 2014 was retrieved by computers. The number of single Chinese herbal medicine and the pharmacologic action features of active ingredients (or extracts) were statistically concluded. Results A total of 279 articles were retrieved, including 67 kinds of single Chinese herbal medicine, among which 8 were used to treat AFLD, 45 were used to treat NAFLD, and 14 were used to treat AFLD and NAFLD simultaneously. Pharmacologic action features of the medicine for AFLD mainly included reducing lipid, protecting liver, antioxidation, and anti-inflammation. Pharmacologic action features of the medicine for NAFLD had the effects of improving insulin resistance additionally.Conclusion Chinese herbal medicine for the treatment of AFLD and NAFLD shows significant efficacy, having the features of multiple pathways and liver damage resistance, which provide references for clinical treatment of fatty liver.
