Correlation study of the 24-hour ambulatory systolic blood pressure and carotid intima-media thickness in the elderly
10.3760/cma.j.issn.1008-6315.2016.07.003
- VernacularTitle:24 h动态收缩压与老年人颈动脉内膜中层厚度的相关性分析
- Author:
Keyu HUANG
;
Chunhui LI
;
Hualing ZHAO
;
Lu SONG
;
Yiming WANG
;
Hui YANG
;
Lingmin MENG
;
Ying ZHU
- Publication Type:Journal Article
- Keywords:
Ambulatory systolic blood pressure;
Carotid intima-media thickness;
Elderly
- From:
Clinical Medicine of China
2016;32(7):585-589
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of the 24?hour ambulatory systolic blood pressure (SBP) and carotid intima?media thickness(CIMT) in the elderly. Methods A total of 2 464 who were more than or equal to 60 years old participants were selected with random sampling in accordance with the inclusion criteria from the retired workers in Tangshan Kailuan Company. Dynamic blood pressure monitoring, neck vascular ultrasound and other examination were performed for the participants. . Multivariable linear regression analysis was used to analyze correlation between the SBP of 24?hour, daytime and nightime with CIMT, respectively. Results ( 1) The observation population was divided into three groups according to the tertiles of SBP of 24?hour, daytime and nightime, respectively. With the levels of different SBPs inceasing, CIMT values thickened markedly ( P<0. 01 ) . ( 2 ) Multivariable linear regression analysis showed that after adjusting for confounding factors,the SBP of 24?hour,daytime and nightime associated with CIMT positively and linearly(P<0. 05),and regression coefficient(95%CI) were 0. 022(0. 009-0. 035), 0. 021(0. 008-0. 035), 0. 019 ( 0. 006-0. 032) respectively. In addition,clinic SBP step into the multivariable linear regression,and regression coefficient ( 95%CI ) were 0. 016 ( 0. 003-0. 029 ) , 0. 016 ( 0. 003-0. 030 ) , 0. 019 ( 0. 007-0. 032 ) , respectively. Conclusion The effect of increased 24?hour ambulatory SBP on CIMT was greater than the clinic SBP. Active monitoring of 24 h ambulatory blood pressure and maintaining a low level of blood pressure is essential for preventing and delaying atherosclerosis.
