Multiple measures to improve perioperative antimicrobial use in typeⅠin-cision operation
10.3969/j.issn.1671-9638.2016.06.015
- VernacularTitle:多项举措改善Ⅰ类切口手术围手术期抗菌药物应用
- Author:
Juan LIU
;
Zhuoping TIAN
;
Shaoming ZHANG
;
Chun CHENG
;
Guoping CHEN
;
Hong YU
- Publication Type:Journal Article
- Keywords:
antimicrobial agent;
type Ⅰ incision operation;
perioperative period;
antimicrobial prophylaxis;
rational antimicrobial use
- From:
Chinese Journal of Infection Control
2016;15(6):422-425
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of multiple intervention measures on perioperative antimicrobial use in pa-tients undergoing typeⅠincision operation in a hospital,and provide basis for rational use of antimicrobial agents. Methods 9 823 patients with type I incision operation in April and October of 2005-2012 were surveyed retrospectively, data of 2005 was as baseline,from 2006 to 2012,multiple measures,including training,examination,supervision,feed-back,and cooperation of relevant departments were conducted,antimicrobial use before and after intervention was com-pared.Results The qualified rate of perioperative antimicrobial use in patients undergoing typeⅠ incision operation in-creased from 14.20% in 2006 to 92.30% in 2012;the rate of combined use of antimicrobial agents was relatively higher (7.00%-9.00%)in 2006-2009,had a downward trend in 2010- 2012,and decreased to 3.20% in 2012.Types of an-timicrobial agents for prophylactic use in typeⅠincision operation in 2006 and 2007 were similar to that of 2005,the main used antimicrobial agents were cephalosporins,penicillin and it’s compounds,and aminoglycosides;the major antimicrobial prophylaxis in 2008-2012 were the first and second generation cephalosporins,penicillin and it’s compounds.Multivariate non-conditional logistic regression analysis showed that age (40 - 59 years old),departments (orthopedics,general surgery,and ophthalmology),and years (2011 and 2012)were the main influencing factors for the qualified use of antimicrobial agents(all P<0.05).Conclusion Implementation of multiple intervention measures can improve the qualified rate of perioperative antimicrobial use in typeⅠ incision operation,reduce types of antimicrobial use and rate of combined antimicrobial use.
