Biocompatibility of modified Kugel mesh in mesh plug tension-free hernioplasty
10.3969/j.issn.2095-4344.2016.25.002
- VernacularTitle:Modified kugel补片疝环充填式无张力疝修补的生物相容性
- Author:
Qingguang WANG
;
Yanhong WANG
;
Caikun ZHANG
;
Haoying ZHANG
;
Fanzhong KONG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2016;20(25):3659-3664
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Mesh plug tension-free hernioplasty is commonly used for inguinal hernia. In the operation, different mesh materials can be selected, among which the modified Kugel mesh is extensively applied. OBJECTIVE: To observe the biocompatibility of modified Kugel mesh in mesh plug tension-free hernioplasty for inguinal hernia. METHODS: Total y 79 cases of inguinal hernia were treated by mesh plug tension-free hernioplasty. The patients were randomly divided into observation group repaired with Bard mesh (modified Kuge) (n=38) and control group repaired with Prolene mesh (n=41). After 12-month fol ow-up, levels of interleukin 6, C-reactive protein and tumor necrosis factor α were detected and compared before and after treatment;adverse events, including wound infection or infection caused by the mesh in the two groups were recorded. RESULTS AND CONCLUSION: Levels of interleukin 6, C-reactive protein and tumor necrosis factor α in the two groups were significantly decreased after treatment than before treatment (P < 0.05). No wound infection or infection caused by the mesh appeared in both two groups. Although scrotum effusion occurred in two cases of each group, their outcomes al improved significantly after active puncture and suction treatment without other serious problems. No recurrence was found during the 12-month fol ow-up. These results show that the modified Kugel mesh has good biocompatibility in mesh plug tension-free hernioplasty for inguinal hernia.
