The Research Progress of Application of Epigenetics in Forensic Science
- VernacularTitle:表观遗传学在法医学中的应用研究进展
- Author:
Lijuan ZHAO
;
Haodong LIU
;
Shengjie NIE
;
Aiting NIE
;
Min RAO
;
Liping HU
- Publication Type:Journal Article
- Keywords:
Epigenetics;
Forensic science;
Paternity testing
- From:
Journal of Kunming Medical University
2016;37(5):123-127
- CountryChina
- Language:Chinese
-
Abstract:
Epigenetics is the study of heritable changes in gene expression other than the changes in the underlying DNA sequence. Such changes include DNA methylation,genomic imprinting,X chromosome inactivation and non-coding RNA regulation. Recent progresses on epigenetics offer new ideas to tackling these problems in forensic science,including determination of the necessary allele in paternity,identification of fetal paternity testing in embryonic period,discrimination of identical twins,origination analysis of tissue,and individual age estimation. This review focuses on the main concept of epigenetics and its application in the field of forensic science.
