Effects of Aging on Arterial Stiffness in Normotensives
- Author:
Huong Thi Thu Duong
- Publication Type:Journal Article
- Keywords:
Arterial stiffness;
Carotid-femoral pulse wave velocity (PWV)
- MeSH:
Arterial stiffness;
Carotid-femoral pulse wave velocity (PWV)
- From:Journal of Medical Research
2008;0(1):102-107
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Introduction: Recent researches have determined that decreased arterial elasticity by age is one of the Cardiovascular risk factors. The modification of arterial elasticity can be evaluated accurately by measuring PWV.\r\n', u'Objectives: To determine the age - related change in the arterial stiffness in healthy people and factors that change the arterial stiffness. \r\n', u'Subjects and methods: The study group consisted of 123 normotensive subjects, including 65 men and 58 women (mean age 51.2 \xb1 13.9 years). Aortic elasticity was assessed by measuring carotid - femoral pulse PWV using a Complior Colson device with 2 pressure transducers.\r\n', u'Results: The mean PWV in both gender groups was 10.2 \xb1 1.6 m/s. There was no significant difference in both the right and the left side of the body, as well as genders regarding PWV calculation. PWV was correlated with age (r = 0.56) and mean blood pressure index (r = 0.6). If PWV was measured on the left side, subjects with plaques in common carotid artery (proved by echo) had a higher PWV than those without carotid plaque presence. In returns, there was no significant difference in terms of PWV, if it was measured on the right side. The arterial PWV in normal subjects with CT/HDL index of more than 5 is higher than those with CT/HDL index of less than 5. There was no correlation between arterial PWV and hyper - cholesterolemia. \r\n', u'Conclusions: 1. Mean arterial PWV in the healthy subjects was. 10.2 \xb1 1.6 m/s. 2. Arterial PWV had a positive correlation with age, mean blood pressure index and CT/HDL index.\r\n', u'
