Preparation Technology Optimization of Hongteng Decoction Hollow Suppositories by Orthogonal Test
- VernacularTitle:正交试验法优选红藤汤中空栓的制备工艺
- Author:
Defeng LUO
;
Fangxiang ZHANG
;
Fen WANG
;
Jingjing QI
;
Zhenhong ZOU
- Publication Type:Journal Article
- Keywords:
Hongteng decoction;
Hollow suppositories;
Preparation process;
Orthogonal test
- From:
China Pharmacist
2016;19(5):1006-1008
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish an optimum preparation process for Hongteng decoction hollow suppositories. Methods:An orthogonal design was performed to screen the proportion of drug and base(A),the temperature of mold filling with drug and base(B)and stripping time(C),and the appearance and melting time were used as the indices ,the best preparation technology of the hollow suppositories was optimized. Results:The optimum preparation technology of the hollow suppositories was as follows:the proportion of drug and base was 1 ∶2,the filling temperature was 40℃,and the stripping time was 30 min. Conclusion:The optimum preparation technology of Hongteng decoction hollow suppositories is simple and feasible.