Retinal Hemodynamic Study using a Scanning Laser Ophthalmoscope in Diabetic Retinopahty.
- Author:
Jun Seop LEE
1
;
Yun Sik YANG
;
Jae Duck KIM
Author Information
1. Department of Ophthalmology, College of Medicine, Wonkwang University, Korea.
- Publication Type:Original Article
- Keywords:
Diabetic retinopathy;
Microcirculation;
Macrocirculation;
SLO;
Venous lamina flow time
- MeSH:
Arm;
Capillaries;
Diabetic Retinopathy;
Fluorescein;
Hemodynamics*;
Leukocytes;
Microcirculation;
Ophthalmoscopes*;
Retinaldehyde*
- From:Journal of the Korean Ophthalmological Society
1995;36(2):279-284
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To investigate retinal hemodynamics in diabetic retinopathy, the perifoveral capillary leukocyte velocity for retinal microcirculation was measured in eyes of 16 control. 12 non-proliferative diabetic retinopathy(NPDR) and 10 proliferative diabetic retinopathy(PDR) on the video fluorescein angiogram using a scanning laser ophthalmoscope(SLO 101, Rod-enstock, Munich, Germany) in 20 degrees retinal field. And the times of arm to retinal circulation, arterio-venous circulation and venous lamina flow for retinal macrocirculation were also measured in eyes of 18 control, 16 NPDR and 10 PDR in 40 degrees retinal field. There was not any statistically significant difference between control eyes(140.62 +/- 34.11 pixels/see, 1.21 +/- 0.29 mm/sec) and NPDR eyes(133.98 +/- 31.85 pixels/sec, 1.15 +/- 0.27 mm/sec) in mean perifoveal capillary leukocyte velocity(p=0.60). But it was significantly decreased in PDR eyes(108.80 +/- 26.19 pixels/see, 0.94 +/- 0.23 mm/sec) compared with control(p=0.01) and NPDR eyes(p=0.05). The were not any significant differences in the times of arm to retinal and arterio-venous circulation respectively(p>0.05) among the eyes of control(12.09 +/- 1.41 sec, 2.41 +/- 0.86 sec), NPDR(12.66 +/- 1.42 see, 2.32 +/- 0.96 sec) and PDR(12.90 +/- 1.51 see, 2.54 +/- 0.94 sec). But the venous lamina flow time was significantly decreased in eyes of NPDR(6.91 +/- 2.32 see, p=0.02) and PDR(7.03 +/- 1.89 sec, p=0.01) compared with that of control(5.46 +/- 1.18 see). These results indicate that a significant retinal microcirculatory deficit exists in the eyes of PDR, and venous lamina flow time may be a good index of retinal macrocirculatory deficit in diabetic retinopathy.
