Localization of parathyroid glands with intravenous low-dose methylene blue in thyroidectomy
10.16066/j.1672-7002.2016.05.001
- VernacularTitle:经静脉低剂量亚甲蓝甲状旁腺定位在甲状腺手术中的初步应用
- Author:
Qi ZHONG
;
Jugao FANG
;
Hongzhi MA
;
Pingdong LI
;
Ling FENG
- Publication Type:Journal Article
- Keywords:
Methylene Blue;
Parathyroid Glands;
Surgical Procedures,Operative;
Thyroid Neoplasms;
thyroidectomy
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2016;23(5):247-249
- CountryChina
- Language:Chinese
-
Abstract:
[ABSTRACT]OBJECTIVETo explore the efficacy and safety of localization for parathyroid glands with intravenous low dosage of methylene blue in thyroidectomy. METHODSWe retrospectively reviewed the clinical data of 41 patients who suffered from thyroid papillary carcinoma between Aug, 2014 and Jan, 2015 (9 males and 32 females, with a median age of 46 years). Thirty eight patients underwent primary thyroidectomy and 3 patients underwent second operation. A variety of thyroidectomy was performed in all patients, and who also underwent intravenous (3-4) mg/kg methylene blue in operation. RESULTSEighty four parathyroid glands were stained. Among 39 patients who's parathyroid glands were stained, the mean dyeing time was (31.27±9.41) min. Dyeing rates and dyeing time were not significantly different between 3 mg/kg group and 4 mg/kg group (t=0.24 and 0.20, all P>0.05). None of patients had the hypoparathyroidism problem such as peri-oral numbness, tingling, muscle aches and spasms. According to postoperative monitoring of parathyroid hormone, all of patients had no permanent hypofunction of the parathyroid gland. Neurotoxic effects and other serious side effects were not observed in all patients. CONCLUSIONIntravenous low-dose methylene blue in thyroidectomy is a safe, easy, and effective technique that facilitates rapid identification of parathyroid gland.
