Clinical analysis on the endoscopic or endoscopy-assisted treatment for the malignant transformation of sinonasal inverted papilloma
10.16066/j.1672-7002.2016.03.008
- VernacularTitle:内镜或内镜辅助下治疗鼻内翻性乳头状瘤恶变的临床分析
- Author:
Huanxin YU
;
Xing LU
;
Gang LIU
- Publication Type:Journal Article
- Keywords:
Papilloma,Inverted;
Endoscopy;
Paranasal Sinus Neoplasms;
Radiotherapy;
Prognosis
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2016;23(3):147-149
- CountryChina
- Language:Chinese
-
Abstract:
[ABSTRACT]OBJECTIVETo investigate malignant transformation of sinonasal inverted papilloma(SNIP) treated by endoscopic or endoscope assisted surgery, in order to analyze its probable prognostic factors and the optimized method.METHODSThe clinical data of 27 cases with malignant transformation of SNIP treated by endoscopic or endoscope assisted surgery from September 2001 to September 2010 were reviewed. According to preoperative imaging examination and UICC staging criteria, 3 cases were T1, 8 cases were T2, 12 cases were T3 and 4 cases were T4. 16 of them received radiotherapy after endoscopic surgery while the other 11 received surgery alone. RESULTSAll cases were confirmed as squamous cell carcinoma pathologically after surgery. The 5-year overall survival rate was 77.8% for all the patients. The 5-year survival rate was 75.0% for surgery alone group, of which 5 cases recurred locally after operation. The 5-year survival rate was 81.8% for surgery combined with radiotherapy group, of which 5 cases recurred locally and 2 cases died from intracranial metastasis.CONCLUSIONEndoscopic or endoscope assisted surgery can be used in the management of malignant transformation of SNIP to improve the quality of life, with the preponderances of desired effect and less complication. Application of radiotherapy after surgery could improve long-term survival rate of the patients.
