Clinico-pathologic features in endometrial carcinoma by the histologic type.
- Author:
Hyuk Jun WOO
1
;
In Ho LEE
;
Sei Jin PARK
;
Won Ki HONG
;
Tae Jin KIM
;
Kyung Taek LIM
;
Jae Uk SHIM
;
Ki Heon LEE
Author Information
1. Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Sungkyunkwan University School of Medicine, Seoul, Korea. 1103khl@hanmail.net
- Publication Type:Original Article
- Keywords:
Endometrial cancer;
Histologic type;
Clinicopatholgic finding
- MeSH:
Endometrial Neoplasms*;
Endometrium;
Female;
Hospitals, General;
Humans;
Menopause;
Mucins;
Recurrence;
Retrospective Studies
- From:Korean Journal of Gynecologic Oncology
2006;17(4):310-315
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The aim of this study was to correlate histologic type with the clinico-pathologic features of endometrial carcinoma. METHODS: A retrospective review was performed of 158 patients with endometrial cancer who had treated surgically at Cheil General Hospital between Jan. 2000 and Dec. 2003. Histologic findings after operation were divided two groups (endometrioid group vs. non-endometrioid group) then compared to each other groups. Clinico-pathologic factors were reviewed, compared and statistically analyzed. RESULTS: Endometrioid group was 112 cases (70.9%) and non-endometrioid group was 46 cases (29.1%). Non-endometrioid group was mucinous; 5 (3.2%), UPSC; 6 (3.8%), clear Cell; 2 (1.3%), mixed; 32 (20.3%), adenosquamous; 1 (0.6%). Non-endometrioid group showed older (p=0.0003) and higher proportion of menopausal women (p=0.0017) than Group 1. But menopause mean age were not diffent between two group. Abnormality in Pap smear and thickness of endometrium (TVS) were not diffent between two group. Non-endometrioid group were significantly associated with higher grade (p=0.0000), deeper myometrial invasion (p=0.0030), larger tumor size (p=0.0006), Lympho-vascular invasion (p=0.0486) and higher recurrence rate (p=0.0369) CONCLUSION: This study revealed non-endometrioid group was significantly associated with older age, menopause status, advanced pathologic features at surgical staging, and high recurrence rate.
