Role and perspective of multiple session stereotactic body radiotherapy in the treatment for spine metastatic tumor
10.3969/J.ISSN.1672-8270.2016.05.047
- VernacularTitle:多分次立体定向放射治疗在椎体转移肿瘤治疗中的作用及应用前景
- Author:
Hao YANG
;
Lin MA
- Publication Type:Journal Article
- Keywords:
Spine metastasis;
Stereotactic body radiation therapy;
Multiple session;
Fractionation schedule
- From:
China Medical Equipment
2016;13(5):151-155
- CountryChina
- Language:Chinese
-
Abstract:
Spine metastasis stereotactic body radiation therapy delivers conformal high radiation dose to the tumor target, and steep falloff dose gradients protect adjacent normal structures, especially spinal cord. Some studies demonstrated stereotactic body radiation therapy for metastatic tumors of the spine is safe and clinically effective. This technique markedly improved local control with an excellent symptomatic response compared with conventional external beam radiation therapy techniques, and is beginning to change the treatment paradigms for metastatic spine disease both as post-operative adjuvant therapy and primary definitive local treatment. Although the technique is being increasingly used in clinical practice, the optimal fractionation schedule remains uncertain. Based on the research of radiobiologic principles, radiological physics and clinical data, multiple session stereotactic body radiation therapy has some advantage in clinic.
