Study on the reliability of CardioChek PA for measuring lipid profile
10.3969/j.issn.1671-167X.2016.03.025
- VernacularTitle:血脂快速分析仪检测血脂的可靠性研究
- Author:
Ying GAO
;
Chenggang ZHU
;
Naqiong WU
;
Yuanlin GUO
;
Geng LIU
;
Qian DONG
;
Jianjun LI
- Publication Type:Journal Article
- Keywords:
Dyslipidemias;
Point-of-care testing;
Cardiovascular diseases
- From:
Journal of Peking University(Health Sciences)
2016;48(3):523-528
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical correlation between the CardioChek PA analyzer (CCPA)and a clinical laboratory reference method to use for screening program purposes.Methods:Fasting blood samples were collected on 325 patients (age:23 -86 years).One venous sample was col-lected using a serum tube for the evaluation on a Beckman reference analyzer.A second venous sample was collected in a lithium heparin tube and was evaluated on the CCPA analyzer.Linear regression analy-ses and Bland-Altman method were performed for each measured analyte:total cholesterol (TC),high density lipoprotein-cholesterol (HDL-C),triglycerides (TG)and low density lipoprotein-cholesterol (LDL-C).Results:Our results demonstrated a good clinical agreement for TC,HDL-C,TG and LDL-C (97.0%,92.9%,92.4% and 83.7%)in comparison with the CCPA to the reference analyzer.The correlation coefficients were 0.875,0.81 3,0.91 0,0.864,respectively.P values all <0.001 .There was no significant difference in the detection rate of hyperlipidemia in TC,HDL-C and LDL-C.Conclu-sion:We have identified the pre-analytic phase as an important step to guarantee the quality of results and indicated that the CCPA is a reliable lipid point-of-care testing system that can be used for the appli-cation of clinical screening anywhere.
